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ACTLipo® Extruders generate homogeneous populations of unilamellar vesicles (liposomes) without need for solvents or detergents. A simple, one-step procedure, extrusion produces liposomes by forcing aqueous suspensions of lipid through polycarbonate filters with defined pore size. This relatively gentle process exposes formulations to moderate pressures of 100-700 psi at controlled temperatures, contrasting with homogenization where temperatures fluctuate and pressures often exceed 18,000 psi.


The ACTLipo® Extruder is the industry standard for the preparation of laboratory-scale liposome formulations. We offer 5 mL small-scale unit up to 100 and 2000 mL units to facilitate scale-up and GMP production of early-stage clinical products. Also, 142 and 293 mm stand-alone filter holders have introduced to support large-scale batch preparation under cGMP, using both nitrogen pressure and pharmaceutical-grade pumps.

 اکسترودر (هموژن‌ساز) لیپوزوم

ACTLipo® Extruders offer advantages over alternative lipid manufacturing strategies:
• Manufactured from high grade stainless steel with no moving parts
• Readily controlled homogeneous particle size
• Achievable high trapping efficiencies
• Wide variety of lipid compositions
• No product volume restrictions.
• Low operating costs
• Easy-to-use equipment
ACTLipo® technology is the equipment of choice for seamless scale-up from research to clinical manufacturing.


Keywords: Liposome Extruder; Liposome Homogenizer; Homogeneous Liposomes; Unilamellar Liposome; Homogeneous populations of unilamellar vesicles (liposomes); Nano Liposome; Easy to use equipment; Low operating costs; Guaranteed; Testimonial